ABSTRACT
On December 13, 2020, Yutian County People's hospital reported one imported malaria case in Hotan, Xinjiang. The patient had worked and lived in Yaounde, Cameroon, from January to September 2020. He was infected with malaria twice in March and May 2020. Antimalarial treatment was administrated by the team doctor for 2-3 days in each treatment. The treatment was stopped after the symptoms improved. The patient returned to China on September 16 and was hospitalized on December 13 due to a high fever of 39! and upper respiratory symptoms. Multiple detections of COVID-19 nucleic acid showed negative results. Peripheral blood from the patient was taken for Plasmodium rapid diagnostic test (RDT), which showed a positive result suggesting non Plasmodium falciparum infection. Ring stage P. ovale was found in the blood smear. Nested PCR showed positive for P. ovale. A diagnosis of imported ovale malaria was made. The patient was administrated with 4 dihydroartemisinin piperaquine tablets and 3 primaquine phosphate tablets daily. The malaria parasite test became negative after 8 days of treatment. The patient was followed up for 3 months after discharge and had no symptoms of chills or fever.Copyright © 2022, National Institute of Parasitic Diseases. All rights reserved.
ABSTRACT
Objective: To analyze the differences between imported malaria before and during the COVID-19 epidemic in Nanning city, and to predict the imported malaria epidemic, so as to provide a basis for future prevention and control strategies. Methods Malaria case data in Nanning city from 2018 to 2021 were collected and divided into two groups. The data from January 1, 2018 to December 31, 2019 were classified as the routine period before COVID-19, and the data from January 1, 2020 to December 31, 2021 were classified as the COVID-19 period. Statistical software was used to analyze the differences between the two groups in basic information, overseas activities, species of infected Plasmodium, diagnosis and treatment. Results The age difference between the two groups was statistically significant (t=2.222, P < 0.05);There was significant difference in the proportion of overseas residence types between the two groups (P < 0.05);There was significant difference in the proportion of parasite species between the two groups (P < 0.05). The proportion of Plasmodium ovale in the COVID-19 period group was higher than that in the routine period group, and the proportion of Plasmodium falciparum was lower than that in the routine period group;There was no significant difference between the two groups in terms of gender proportion, current address category proportion, malaria proportion due to going out for gold, proportion of mild, moderate and severe disease degree, proportion of hospitalization, proportion of standardized treatment, proportion of whole course medication, proportion of cure and length of hospital stay. Conclusions The incidence of imported malaria in Nanning declined significantly during the period of COVID-19, and the proportion of Plasmodium falciparum infection decreased. It is necessary to be vigilant against the outbreak of imported malaria caused by the increase of inbound people with the progress of COVID-19 control.
ABSTRACT
Objective: This paper reports a case of Plasmodium ovale and SARS-CoV-2 coinfection, which was successfully cured under the strategy of early diagnosis, timely antiviral and anti-malarial treatment, offering a reference for clinical diagnosis and treatment of this disease. Methods The epidemiological history, clinical manifestations, treatment status and laboratory results of the case were collected for case analysis.